1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: That is an impurity linked to bortezomib, a proteasome inhibitor Utilized in the remedy of many myeloma. Its synthesis or study is essential for ensuring the purity and safety of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor while in the synthesis of abiraterone acetate, a drug used in the treatment of prostate most cancers by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-ten-1): A key compound during the synthesis of imatinib, a drug that targets unique different types of most cancers, which include Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats many cancers such as breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are intermediates while in the synthesis of gemcitabine, an anti-cancer drug. Their analyze is crucial for optimizing the production course of action and making certain high purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is made use of to treat breast cancer, and these intermediates are involved with its trans-4-Dimethylaminocrotonic acid hydrochloride manufacturing.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Employed in the treatment method of breast most cancers. Various intermediates help in the synthesis of this drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug helpful in treating cancers like ovarian, breast, and lung most cancers.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the cure of colorectal most cancers and small cell lung cancer.
3-Amino-one-hydroxyadamantane (CAS 702-82-nine): This compound is associated with the synthesis of adamantane derivatives, which have a variety of apps, like antiviral Qualities.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for style two diabetic issues that inhibits the enzyme 3 DPP-four to control blood sugar degrees.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved with the synthesis of varied gluconic acid derivatives, that are Utilized in foodstuff, pharmaceutical, and industrial apps.
Canagliflozin Intermediate two: A precursor within the synthesis of canagliflozin, a medication utilized to manage type two diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).